The global fluorescence lifetime imaging microscopy
market, by end-user, is segmented into semiconductor, chemical
industry, medical care, academic institutes, and so on. Fluorescence lifetime
imaging microscopy (FLIM) is a technique utilized to measure the fluorescence
lifetime of molecules. The fluorescence lifetime is the average time a molecule
spends in an excited state before returning to the ground state. This
measurement is a highly quantitative value that can be used to determine
molecular dynamics with nanoscale resolution. FLIM is a standard technique for
determining the lifetimes of fluorescent molecules in cells, tissues and whole
animal models. Fluorescence lifetime imaging microscopy (FLIM) produces an
image based on the differences in the excited state decay rate from a
fluorescent sample. Thus, FLIM is a fluorescence imaging technique where the
contrast is based on the lifetime of individual fluorophores rather than their
emission spectra. The fluorescence lifetime is defined as the average time that
a molecule remains in an excited state prior to returning to the ground state
by emitting a photon.
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Multi-color staining with
fluorescent dyes is actively used for observing the distribution of biological
materials (such as proteins, lipids, nucleic acids, and ions) in the field of
tissue and cell research. The detection technology for fluorescence observation
has advanced to a level at which a single fluorescent dye molecule can be
detected under the best of circumstances. Rising global focus on
nanotechnology, appropriate government and corporate funding and technological
advancements such as super resolution microscopy; high-throughput techniques
and digitization of microscopes are the factors driving the fluorescence
lifetime imaging microscopy market.
However, the high cost of
advanced microscopes; implementation of excise tax by the U.S. government; and
the heavy custom duty with respect to medical devices are hindering the growth
of this market. On the other hand, novel application areas such as optogenetics
and high potential emerging markets such as Middle East, China, and Japan represent
significant growth opportunities for the key players.
Further, time consuming sample
preparation process for advanced microscopes and requirement of high degree of
technical expertise to handle complex microscopes may prove to be a restraint
to the growth of this market during the forecast period. The fluorescence
lifetime imaging microscopy market is segmented on the basis of application and
geography. On the basis of application, the fluorescence lifetime imaging
microscopy market is segmented into North America, Asia Pacific, Europe, Latin
America and Middle East & Africa. North America is expected to account for
the largest share of the microscopy market, followed by Europe.
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However, Asia Pacific is expected
to register a higher growth rate during the forecast period, owing to huge
investment opportunities in this region. The growth of the fluorescence
lifetime imaging microscopy market in the Asia Pacific region will be attributed
toIndia, Australia, China,and countries in the Middle East. The key players of
fluorescence lifetime imaging microscopy are Leica microsystems, Brucker, Fly
limited, Olympus Corporation, Asylum, Japanese Electronics Co. Ltd., Micro
engineering in Denmark, Hitachi High-Technologies Corporation, Carl Zeiss AG
and Nikon Corporation.
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