Wednesday 26 September 2018

Protein Kinase Inhibitors Market Growth Rate, Revenue and Market Overview Forecast 2025

26 September 2018: Global Protein Kinase Inhibitor Market is anticipated to grow at a higher CAGR in the forecast period. The global market encompasses extensive R&D and favorable funding from private sector that propels the market growth.  Generally, a protein kinase is a kinase enzyme that alters other proteins by chemically addition of phosphate groups to them. Protein kinases are indispensable for various cell processes. These enzymes catalyze phosphorylation of various other cellular substrates. Phosphorylation regulates cellular functions in return. However, protein kinases can be deregulated under pathological conditions resulting into variations in phosphorylation and uncontrolled cell division, apoptosis inhibition and other abnormalities. 

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Clinically, protein kinases help in understanding inter and intra-cellular molecular interactions, and also explains the role of multiple cellular biochemical networks and clarify unknown details of different cell processes such as division and metabolism. Characteristically, protein kinase inhibitors are chemically assorted and possess low-molecular weight. Along with protein kinases with ATP substrate, there exists a group of ATP non-competitive inhibitors which describe a group of peptide inhibitors of protein kinases. 

On a commercial scale, protein kinase inhibitors help in diagnosing cancer patients and also the rise in demand for custom treatments has been a prime feature in the growth of protein kinase inhibitor market. Overall, with the product innovation and novel therapies the protein kinase market is expected to rise at a higher CAGR in the international market.  Protein kinase inhibitor industry is driven by factor such as rising R&D activities against cancer in developed countries. Additionally, technological innovations and data-driven customizations to fulfill consumer demand for efficiency and accurate outcome also propel the market growth in the forecast period. Moreover, protein kinases as anti-cancer drugs account for a significant share in the global market. 

Protein Kinase inhibitor industry geographically spans North America, Latin America, Asia-Pacific, Europe, Middle-East and Africa. North America dominates the global market in terms of value. Also, factors such as rising R&D activities in this region propel the market growth in the forecast period. Europe is anticipated to rise at a tremendous CAGR in the forecast period owing to extensive research on cancer and cancerous cells. 

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APAC regions are anticipated to rise at a higher CAGR in the forecast period owing to rising prevalence of cancer and need for novel therapies. Middle-East and African protein kinase inhibitor industry is expected to rise at a moderate CAGR owing to low medical infrastructure and less R&D activities. 

The key players in the protein kinase inhibitor industry include Pfizer, Alnylam Pharmaceuticals, Allergan, Amgen, Biocon, Angstorm Pharmaceuticals, Bionomics, Acceleron Pharma, CASI Pharmaceuticals, Celegene Corporation, Enzon Pharmaceuticals, Five Prime Therapeutics, Fujifilm Kyowa Kirin Biologics, Hetero Drugs, Genentech, ImClone Systems, Genexine, Intas Pharmaceuticals, Kyowa Hakko Kirin, Levolta Pharmaceuticals, Marsala Biotech, Neumedicines, Novartis, Onyx Pharmaceuticals, and Oncobiologics.

1 comment:

  1. EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM), which inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM), prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. KYL

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